Chemical Informatics Letters: The latest news in chemical informatics, links to relevant web sites, analysis and discussion.
Chemistry Software for Apple Macintosh: Software resources for chemists using Apple Macintosh.
Computational Chemistry List - Software: Archive of chemistry software for Unix, MS-DOS, Windows, Mac. Includes source code in most cases.
Linux4Chemistry: An up-to-date directory of Linux software for chemistry. Lists more than 100 free and commercial programs.
QSAR Software: A QSAR (Quantitative Structure Activity Relationship) relevant link collection of 'The International QSAR Society'.
Scientific Applications for Linux: Chemistry: Descriptions, screen shots, licensing information, and links for over 200 chemical programs for Linux.
The OpenScience Project: Chemistry: A collection of links for Open Source scientific software projects.
Tom's Free Chemistry Software Reference: Frequently-updated searchable alphabetical index of free Chemistry software. Features a search engine.