| Down Syndrome Liverpool: Local support group for those with DS, their parents and carers. A registered charity in the UK |
| Down Syndrome Association of Western Australia: Works to support the community to develop the potential of people with Down syndrome (Trisomy 21) to live a valued life. |
| Down Syndrome in the Broward County Community: Local information for parents and families with children who have Down syndrome. Specifically in the Broward County area of the State of Florida. |
| Down Syndrome Resource Center (DSRC): A not-for-profit support and interest group for people with Down syndrome in the Capital Region of New York state. Articles, membership, and events. |
| Down's Syndrome Association, Lincolnshire Branch: Poems and stories, articles, and book reviews. |
| Down's Syndrome Association, London Branch, UK: Support group for parents and carers of people with Down's Syndrome. |
| DS Network, Inc.: Includes bulletin board and events calendar. |
| Eastern Pennsylvania Down Syndrome Center: Includes a message board and chat room, also a list of their coming events. |
| Edmonton Down Syndrome Society: An organization committed to supporting people and their families. Features membership information, workshops and seminars. Alberta, Canada. |
| Families Dealing With Down Syndrome: A family oriented e-mail group that is geared towards the love, support and health of children with Down Syndrome. |
| Gold Coast Down Syndrome Organization: In Palm Beach county, FL. Provides a FAQ and inclusion information. |
| International Mosaic Down Syndrome Association: A non profit organization to help and support parents around the world in research and meeting new people. Includes research, education and contact details. |
| Jesus and Downs: Message board to connect Christian parents who have a loved one with Down Syndrome. |
| Mosaic Down Syndrome UK: A support group for parents of children born with Mosaic Down Syndrome. Based in the UK, the group warmly welcomes parents from outside the UK. |
| Oshkosh Down Syndrome Group: For parents of a down syndrome child, located in Oshkosh, Wisconsin. Includes newsletter, links and a photograph gallery. |
| Piedmont Down Syndrome Support Network: Information about the parent support group for Winston-Salem, North Carolina. |
| Positively Down: Parent led resource, support and social group for families of children with Down syndrome in and around London Borough of Richmond, UK |
| The Ups of Downs: Dedicated to parents of children with Down Syndrome. Membership is free and open to anyone. Includes information about Downs, education and literature. |
| Triangle Down Syndrome Network: For families in central North Carolina. Online newsletter and stories about their kids. |
| Trisomy 21 Online Community: For all those touched by people with all three forms of Trisomy 21. Community includes message forums, chat room, information for parents who have just found out their child has Trisomy 21, pictures and many other information pages and links. |
| Uno Mas Down Syndrome Online: Supportive online group of parents & friends of kids with Down Syndrome. Message Boards and Personal Stories. Hundreds of photos. |
| Ups & Downs Calgary Down Syndrome Association: Includes newsletters and discussion. |
| Yahoo! Groups : Christian-DS-Parents: Mailing list for parents of Down Syndrome children who are practicing Christians. |
| [HealthBoards.com] Down Syndrome Message Board: The archives of this board. |