| Association of Greater Cincinnati for Down Syndrome: Information on the programs they offer, and upcoming events. |
| Central Illinois Down Syndrome Organization (CIDSO): Contains a list of the organization's goals, and information about their library and events. |
| Colorado Springs Down Syndrome Association: Information about the organization as well as the disease. Includes membership, events, a photo album, articles and links. |
| Connecticut Down Syndrome Congress: Dedicated to improving the lives of persons with Down syndrome. Includes information on scholarships, and resources. |
| Down Syndrome Association of Greater New Orleans: Has photo gallery and a list of the association's board members. |
| Down Syndrome Association of NSW Australia: Articles, newsletters, stories & photos for people with Down syndrome, their families, friends, educators and health care professionals. |
| Down Syndrome Association of Toronto: Information on education and health as it relates to Down Syndrome. |
| Down Syndrome Catalana Foundation: Information about the foundation. |
| Down Syndrome Research Foundation: Information on the Antioxidant Research Project and raising funds for it. Includes news, health issues, research, events, education, alternate therapies and contact details. |
| Down Syndrome Research Foundation and Resource Centre: Articles on psychological, social, and physical development, also on health issues. Research project reports and summaries. |
| Down Syndrome Research Online Advocacy Group: Information on clinical, biomedical, and scientific research into Down syndrome. |
| DSAOC- Down Syndrome Association of Orange County: Down Syndrome Association of Orange County, based in Santa Ana, California. |
| Hawkeye Area Down Syndrome Association: The organizations' goals, and also how to get on the MR Waiver List. |
| Initiative for People with Down's Syndrome: Includes photos of children from around the world, and an online exhibition entitled "Variety Enriches Our World." |
| Jane and Richard Thomas Center for Down Syndrome: at Cincinnati Children's Hospital Medical Center offers innovative approaches to caring for children with Down syndrome. |
| Mile High Down Syndrome Association: Has a section on research, as well as examples of the Kids 'R Kids calendar. |
| National Association for Down Syndrome: In Chicago. Includes a bulletin board. |
| North Country Down Syndrome Association: Provides information about the association, which is located in Plattsburgh, NY, serving Clinton and Essex Counties. Also has pictures. |
| Northern New England Down Syndrome Congress: Non-profit organization of families, professionals, and others who are interested in sharing knowledge and the experience of Down Syndrome. |
| Riverbend Down Syndrome Parent Support Group: Resources and abstracts for parents and professionals on communication, early intervention, therapies, medicine, literacy, medical issues, mathematics, vitamins and other supplements. |
| Sharing Down Syndrome Arizona: Has a listing of Down Syndrome events in their area, also many poems and stories. |
| The Down Syndrome Educational Trust: Based in the United Kingdom. Working to advance the development and education of individuals with Down syndrome |