archivemail: Python tool for detecting and compressing older e-mail messages.
BSD Vacation V2: RFP-compliant vacation mailer, designed to replace the standard Sendmail vacation program.
Fetchmail: Fetchmail is a free, full-featured, robust, well-documented remote-mail retrieval and forwarding utility intended to be used over on-demand TCP/IP links (such as SLIP or PPP connections).
maildrop - mail delivery agent with filtering: Maildrop reads a mail message from standard input, then delivers the message to your mailbox. maildrop will optionally read instructions from a file, which describes how to filter incoming mail. Instructions can be provided having mail delivered to alternate mailboxes, or forwarded using a structured filtering language.
Mailfilt, by Mike Fisk (Unix/Perl): Mailfilt is a procmail-like Perl application for filtering your mail. (Last updated sometime in 1995 ...)
Pygmy: A GNOME mail client written in Python. Pygmy supports attachments and MIME messages, both in the message composer and in the message viewer.
The Fetchmail FAQ: Frequently asked questions about fetchmail.
Vacation Auto-Reply (Unix): Simple instructions for one variant of the vacation(1) program on Unix. (This doesn't appear to be the most standard version, but the general instructions look relatively ok.)